Reduced Left Angular Gyrus Volume in First-Episode Schizophrenia

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Reduced left angular gyrus volume in first-episode schizophrenia.

OBJECTIVE Research suggests that the normal left-greater-than-right angular gyrus volume asymmetry is reversed in chronic schizophrenia. The authors examined whether angular gyrus volume and asymmetry were abnormal in patients with first-episode schizophrenia. METHOD Magnetic resonance imaging scans were obtained from 14 inpatients at their first hospitalization for psychosis and 14 normal co...

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T he article by Velakoulis et al 1 reported the important finding of hippocampal volume reduction in first-episode schizophrenia and interpreted it as evidence in support of a neurodevelopmental model of this disorder. The authors stated that " no [pre-vious] studies have examined the specificity of this finding to first-episode schizophrenia, compared with first-episode affective psychosis. " ...

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Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia.

OBJECTIVE Smaller temporal lobe cortical gray matter volumes, including the left superior temporal gyrus, have been reported in magnetic resonance imaging (MRI) studies of patients with chronic schizophrenia and, more recently, in patients with first-episode schizophrenia. However, it remains unknown whether there are progressive decreases in temporal lobe cortical gray matter volumes in patien...

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ژورنال

عنوان ژورنال: American Journal of Psychiatry

سال: 2005

ISSN: 0002-953X,1535-7228

DOI: 10.1176/appi.ajp.162.8.1539